| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_37b36726b8c2d3a2fe627ab8caf1e052
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_43a72884e25aaecffebe0942132d704f |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P35-04
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N33-574
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K16-30
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K16-28
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-113 |
| filingDate |
2013-11-07-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate |
2019-04-23-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_7495d595c078031869a1220a38633f0b
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_162f952822666655d44e6955d8efd2df
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_feecdd8d6e6c8436779ec5a60b2b494e
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_bbf222fee9a86c27329f0a584b3bb01c |
| publicationDate |
2019-04-23-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
ES-2710174-T3 |
| titleOfInvention |
Methods and pharmaceutical compositions for the treatment of bone metastasis |
| abstract |
An agent selected from the group consisting of an anti-ROBO4 antibody, a ROBO4 decoy polypeptide and an inhibitor of ROBO4 expression for use in a method of preventing or treating bone metastasis in a subject in need thereof wherein the inhibitor of the expression of ROBO4 is selected from the group consisting of ROBO4 siRNAs, ROBO4 shRNAs, ROBO4 ribozymes and ROBO4 antisense oligonucleotides and wherein the ROBO4 decoy polypeptide comprises the extracellular domain of ROBO4. |
| priorityDate |
2012-11-08-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |