Predicate |
Object |
assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_74b7b50944d8e1960440fb1f5440b7fd |
classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K2039-505 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K2317-24 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K2317-73 |
classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P7-06 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P1-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P11-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P13-08 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P13-12 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P15-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P17-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P17-10 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P19-02 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P21-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P25-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K16-28 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K16-2803 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K16-30 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P29-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P3-10 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P31-12 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P35-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P35-02 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P37-02 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P37-06 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P43-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P5-14 |
classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K16-30 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K16-28 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K39-00 |
filingDate |
2007-01-11-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
grantDate |
2019-04-17-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_2a36341dc22d8dccbaa1074ad55210c8 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_2c9375b963976ca8ad134b2e3d0b4629 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_0cbfc9552b5f98c1c9b4c0759652b20b http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_f453aa0bde2a859fe420f00789b64a64 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_baaf258a1a6d0ccee9f998ffcc744e8d |
publicationDate |
2019-04-17-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber |
ES-2709672-T3 |
titleOfInvention |
Antibodies for OX-2 / CD200 and uses thereof |
abstract |
An anti-CD200 antibody, wherein the anti-CD200 antibody: (i) inhibits the interaction between CD200 and CD200R; and (ii) comprises a variant Fc constant region that: (a) is a variant Fc constant region in which the CH1 and hinge regions are from human IgG2 and the CH2 and CH3 regions are from human IgG4; (b) comprises one or both of: (A) a substitution of phenylalanine for alanine at position 234 and (B) a substitution of leucine for alanine at position 235 according to the EU index; (c) comprises a K322A mutation in the CH2 domain according to the EU index; or (d) lacks a hinge region. |
priorityDate |
2006-01-12-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type |
http://data.epo.org/linked-data/def/patent/Publication |