| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_69108fc12b940ede105638f37f06080b |
| classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K2319-92
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K2319-50 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N15-62
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N9-93
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12P21-02
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12P21-06
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K14-195
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K16-18 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K16-18 |
| filingDate |
2013-06-24-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate |
2019-04-16-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_b445c967f70dfd686c34059c2e6dd0c3
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_87609c2de0454147db86bbbc0ef22b15
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_609350ebb5dff185ba133d3d78ff2e32
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_3498588e20d251d8244fca5e862ad73b |
| publicationDate |
2019-04-16-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
ES-2709333-T3 |
| titleOfInvention |
Divine inteins, conjugates and uses thereof |
| abstract |
A method comprising (a) contacting (1) a fusion protein comprising a polypeptide and an N-fragment of divided intein comprising a sequence selected from the group consisting of SEQ ID NO: 1-19, or a variant of the same, in which the variant comprises a sequence selected from the group consisting of SEQ ID NO: 21-38 and 761 and (2) a fragment C of divided intein comprising a sequence selected from the group consisting of SEQ ID NO: 57-74, in which the contact is made under conditions that allow for the attachment of the N fragment of the divided intein to the C fragment of the divided intein to form an intein intermediate; and (b) contacting the intein intermediate with a nucleophile to form a protein and nucleophile conjugate. |
| priorityDate |
2012-06-27-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |