abstract |
A meso-substituted asymmetrically tetrapyrrolic compound comprising two polar and two nonpolar meso-substituents specifically based on the formula: ** Formula ** where the meso-substituents have an A'2B'2 substitution pattern; where B is selected from the group consisting of: ** Formula ** where R2 is a substituent at any meta- or para- position of the phenyl ring selected from the group consisting of OH, -COOH, -COOCH3, -NH2, - COOX, -NHX, -OX, -NH-Y-COOH and CO-Y-NH2; where: X is a polyethylene glycol residue with (CH2CH2O) nCH3 with n = 1-30 or a carbohydrate moiety and Y is a peptide or oligopeptide where n = 1-30. |