| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_633506d7c8863075bf58f012119cdbde |
| classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N2800-56
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N2800-52
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N2800-20
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N2800-7028 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-5743
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P35-04
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P35-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-57484
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-68 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N33-574 |
| filingDate |
2015-11-05-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate |
2019-03-26-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_f7bf439227fc5b958ff210b0a1e5bdb3
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_88ccef0ab053a01f48cc5a150911c5bb
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_640843cfcad4cbd0e7e795a7a991dd39 |
| publicationDate |
2019-03-26-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
ES-2705614-T3 |
| titleOfInvention |
Biomarkers for disease progression in melanoma |
| abstract |
An in vitro method for determining if a subject with melanoma has a higher risk of metastasis, the method comprises: (i) determining the expression of Ambra-1 and Loricrin in a tissue sample obtained from the subject, wherein the tissue sample comprises tissue that covers a primary melanoma; and (ii) compare the expression obtained in (i) with a reference tissue or the levels obtained therefrom, where a decrease in the expression of Ambra-1 and Loricrina in the tissue sample compared to the tissue or Reference levels, or a loss of expression of Ambra-1 and Loricrin in the tissue sample, is indicative of an increased risk of metastasis. |
| priorityDate |
2014-11-10-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |