http://rdf.ncbi.nlm.nih.gov/pubchem/patent/ES-270561-A1
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_6b6fc801b5bfe5304ffa40d938db6e09 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07C317-46 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07C323-62 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07C65-26 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07C65-21 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07C65-28 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07C323-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07C63-72 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07C65-24 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C63-72 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C65-26 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C323-62 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C65-24 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C65-21 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C317-46 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C65-28 |
| filingDate | 1961-09-05-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationDate | 1962-02-16-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | ES-270561-A1 |
| titleOfInvention | PROCEDURE FOR THE PREPARATION OF NEW DERIVATIVES OF THE ALQUILBENZOICO ACID |
| abstract | Process for the preparation of new alkylbenzoic acid derivatives, of the general formula ** (See formula) ** in which R 1 means an alkoxy, cycloalkoyl, aralkoxy, aryloxy, acyloxy radical, a halogen atom, a trifluoromethyl group or a hydroxyl group, R2 means hydrogen, a halogen atom or an alkyl group, and R3 means a carboxyalkoxyalkyl, alkoxyalkyl, cycloalkoxyalkyl, alkenyloxyalkyl, alkynyloxyalkyl, halogenalkoxyalkyl, hydroxyalkoxyalkyl or aralkoxyalkyl radical, in which case the oxygen atom ethereally bound to these radicals may be substituted by S, SO, SO2, and furthermore a hydroxyalkyl, acyloxyalkyl radical, acylthioalkyl, aryloxyalkyl, arylthioalkyl, heteroyloxyalkyl or heterothioalkyl, as well as its non-toxic and pharmaceutically acceptable salts with bases, characterized in that the sodium salt of an appropriate hydroxymethylbenzoic acid derivative of the general formula is reacted ** (See formula) ** in which R1 and R2 have the meaning indicated above, R4 signifies hydrogen, an alkali metal ion or the ammonium ion, a lower alkylamino or alkyl group, and X2 means a sulfur atom or an oxygen atom, with a halogenated derivative of an appropriate organic compound of the general formula ** (See formula) ** in which R5 means a lower alkyl group, a carboxyalkyl, a carboxaryl, alkenyl, alkynyl, cycloalkyl, haloalkyl, hydroxyalkyl, benzyl or phenylethyl group, and X1 has the meaning indicated above, the acid group, optionally bound, of the compound thus obtained, of the general formula is liberated by saponification and/or hydrolysis ** (See formula) ** in which R1, R2, R4, R5 and X2 have the meaning indicated above, and, if desired, the compounds thus obtained, of the general formula I, are transformed with bases into pharmaceutically acceptable salts. (Machine-translation by Google Translate, not legally binding) |
| priorityDate | 1960-09-20-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
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