abstract |
An antithrombotic molecule having antiplatelet and anticoagulant activity (APAC) comprising a human plasma protein to which is bound, by a plurality of linker molecules, a plurality of heparin chains each having a MW between 10-21 KDa and furthermore where the amount of said heparin chains attached to said plasma protein is selected from the group consisting of 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 15, and 16. |