http://rdf.ncbi.nlm.nih.gov/pubchem/patent/ES-2699261-T3

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filingDate 2014-05-16-04:00^^<http://www.w3.org/2001/XMLSchema#date>
grantDate 2019-02-08-04:00^^<http://www.w3.org/2001/XMLSchema#date>
inventor http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_d3484d2ba59658e9cab3e8be400135e6
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publicationDate 2019-02-08-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber ES-2699261-T3
titleOfInvention Derivatives of sulfamoylpyrrollamide and its use as medicines for the treatment of hepatitis b
abstract A compound of Formula (ID) ** Formula ** or a stereoisomer or a tautomeric form thereof, where: each X independently represents CR7; Ra, Rb and Rc are independently selected from the group consisting of Hydrogen, Fluoro, Bromo, Chloro, - CHF2, -CF2-methyl, -CH2F, -CF3, -OCF3, -CN, C1-C3 alkyl and C3-C4 cycloalkyl; Rd is Hydrogen or Fluoro; R4 is Hydrogen, C1-C3 alkyl or C3-C4 cycloalkyl; R5 is Hydrogen; R6 is selected from the group consisting of C2-C6 alkyl, (C1-C4 alkyl) -R8 optionally substituted with one or more Fluoro moieties, (C1-C4 alkyl) -R9 optionally substituted with one or more Fluoro moieties, and a saturated ring 3-7 membered mono- or polycyclic optionally containing one or more heteroatoms independently each selected from the group consisting of O, S and N, said 3-7 membered saturated ring or said C2-C6 alkyl optionally substituted with one or more substituents independently selected each from the group consisting of Hydrogen, -OH, Fluoro, oxo, R9, R10 and C1-C4 alkyl optionally substituted with R10; R7 represents Hydrogen, -CN, Fluoro, Chlorine, Bromo, -CHF2, -CF2-methyl, -CH2F, -CF3, C1-C3 alkyl optionally substituted with methoxy, C2-C3 alkenyl or C3-C4 cycloalkyl; R8 represents a 3-7-saturated saturated ring that optionally contains one or more heteroatoms independently each selected from the group consisting of O, S and N, said 3-7-saturated saturated ring being optionally substituted with one or more alkyl moieties C1-C4 optionally substituted with R10; R9 represents C1-C4 alkyloxy, -SO2-methyl, -C (= O) -OR11 or -C (= O) -N (R11) 2; R10 represents -CN, -OH, Fluoro, -CHF2, -CH2F or -CF3; R11 represents hydrogen or C1-C3 alkyl; or a pharmaceutically acceptable salt or solvate thereof, wherein said compound is not ** Formula **
priorityDate 2013-05-17-04:00^^<http://www.w3.org/2001/XMLSchema#date>
type http://data.epo.org/linked-data/def/patent/Publication

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