http://rdf.ncbi.nlm.nih.gov/pubchem/patent/ES-2698518-T3
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_c1432597c4e83d4ec79685539afb3f1d |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G16C10-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-92 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-82 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-5308 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12M1-34 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N33-50 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N33-53 |
| filingDate | 2015-12-11-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 2019-02-05-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_281df11ccf4375cfb4c7de3a9596d9da http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_979130ba04459e89b1b52533a1d6904c |
| publicationDate | 2019-02-05-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | ES-2698518-T3 |
| titleOfInvention | Accurate assay measurement of hydrophobic haptenic analytes |
| abstract | A method of determining an actual concentration of a hydrophobic hapthenic analyte in an unknown sample that is suspected of containing the hydrophobic hapthenic analyte, where it is suspected that the unknown sample contains an interfering substance, the method comprising: (a) performing a first test method in an unknown sample to obtain a measured concentration of the haptenic hydrophobic analyte in the unknown sample and perform a second test method in the unknown sample to obtain a concentration of the interfering substance in the unknown sample; and (b) applying a predetermined correction formula using the measured concentration of the hydrophobic hapthenic analyte and the measured concentration of the interfering substance obtained in step (a) to determine an actual concentration of the hydrophobic haptenic analyte in the unknown sample, in the that the correction formula is predetermined by a method comprising: (i) measuring a concentration of the hydrophobic hapten analyte for at least two different samples using the first assay method and measuring the concentration of the hydrophobic hapten analyte for the at least two different samples using a reference method in which the samples also comprise the interfering substance, (ii) determining a bias between the first test method and the reference method in which the bias is the difference between the concentration of the hydrophobic hapten analyte determined by the reference method and the first test method for c ada shows different; (iii) measuring a concentration of the interfering substance for at least two different samples; and (iv) determining the correction formula by performing a regression analysis using the bias and the concentration of the interfering substance for each of the at least two different samples, in which the regression analysis comprises forming a regression line and using the slope and the intersection of the regression line to form the following correction formula: [An] = [Anm] + (a × [SIm] + b) where: [An] is the actual concentration of the haptenic hydrophobic analyte in the unknown sample, [Anm] is the measured concentration of the hydrophobic hapthenic analyte in the unknown sample, [SIm] is the measured concentration of the interfering substance in the unknown sample, a is the slope of the regression line, and b is the intersection of the regression line. |
| priorityDate | 2014-12-17-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 89.