http://rdf.ncbi.nlm.nih.gov/pubchem/patent/ES-2696848-T3
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_f52c68e4149a6c462b850d4e7cc2b2f9 |
| classificationCPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07J31-003 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07J41-0038 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07J43-003 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K45-06 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-58 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P5-24 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P3-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P29-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P3-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P43-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P35-02 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P35-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P15-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P13-08 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P13-10 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P13-12 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P17-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P11-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P17-14 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P17-08 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P17-10 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P5-24 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07J43-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07J41-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07J31-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-58 |
| filingDate | 2015-09-07-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 2019-01-18-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_f6cb7e73753d29287f67de89ccd1be59 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_2527f9595caea1ec2c8a1be4b9edabe9 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_c131c20b2f2e2afd6eac1343743a144d http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_5ee8715e5120d7663d171e30d7e4e0a4 |
| publicationDate | 2019-01-18-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | ES-2696848-T3 |
| titleOfInvention | Inhibitors of oestra-1,3,5 (10), 16-tetraene AKR1C3 substituted with 3-nitrogen or sulfur |
| abstract | Compounds of the general formula (I) ** Formula ** in which: A represents a group selected from: ** Formula ** in which * indicates the point of attachment of said group with the rest of the molecule; X is a group selected from: ** Formula ** in which * indicates the point of attachment of the group with the rest of the molecule and in which the group is optionally substituted, one or more times, independently of one another, with a substituent selected from halogen, CN, OH, RR2N-, C1-C6 alkyl, C1-C6 haloalkyl, C1-C6 alkoxy, C1-C6 haloalkoxy, in which the C1-C6 alkyl and C1-C6 haloalkyl groups are optionally substituted with OH; R1 is C1-C6 alkyl or C1-C6 haloalkyl, and wherein R1 is optionally substituted with one or two substituents, independently of one another, selected from OH, CN, RO (CO) -, RR2N (CO) -, RR2NSO2-, C1-C6-alkyl (CO) (NH) SO2- or 5-tetrazolyl; R2, R5 are, independently of one another, hydrogen or C1-C6 alkyl, in which the C1-C6 alkyl groups are optionally substituted, one or more times, independently of each other, with halogen, R3, R4 are, independently of one another, C1-C6 alkyl or C1-C6 haloalkyl, and wherein R3 and R4 are optionally substituted with one or two substituents, independently of one another, selected from OH, CN, RO (CO) -, RR2N (CO) -, RR2NSO2-, C1-C6-alkyl (CO) (NH) SO2- or 5-tetrazolyl; R6, R 7, R8, R9 are, independently of one another, C1-C6 alkyl or C1-C6 haloalkyl, and wherein R6, R7, R8 and R9 are optionally substituted with one or two substituents, independently of one of the others selected from OH, CN, RO (CO) -, RR2N (CO) -, RR2NSO2-, C1-C6-alkyl (CO) (NH) SO2- or 5-tetrazolyl; R is hydrogen or a C1-C6 alkyl group; or tautomers, N-oxides, hydrates, solvates, or salts thereof, or a mixture consisting of the above. |
| priorityDate | 2014-09-11-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 706.