| abstract |
A compound of Formula (I): ** Formula ** or a complex, hydrate, solvate, or polymorph, tautomer, geometric isomer, optically active form, or a pharmaceutically acceptable salt thereof, in which: HAR is an annular system heteroaryl of members selected from ** Formula ** R1 in each case is independently selected from H, C1-6 alkyl, CF3 and C3-C5 cycloalkyl; R2 in each case is independently selected from halo, -CN and C1-6 alkyl; R3 in each case is selected from H, C1-6 alkyl, C3-C5 cycloalkyl and CF3; R4 in each case is independently selected from H and C1-6 alkyl; R5 in each case is independently selected from H and C1-6 alkyl; and R6 in each case is independently selected from H and C1-6 alkyl. |