http://rdf.ncbi.nlm.nih.gov/pubchem/patent/ES-2693152-T3
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_e04a9c30b01a6909696dc92e883f241c |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D495-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D487-14 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P17-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P25-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P25-06 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P25-08 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P25-20 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D471-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P3-10 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D519-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-5517 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D487-14 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D471-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D495-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-5517 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D519-00 |
| filingDate | 2012-05-10-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 2018-12-07-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_37ab510851471d5b37ad9b408336165d http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_9c37dec5989ac4cf8ac0b7bafd1486ee http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_cd341cf876e85d0bbefccb9caff369f9 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_d406296e718286c6981665836b8112dd http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_f9ff4ff738fb99471462a6e8a5401cb5 |
| publicationDate | 2018-12-07-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | ES-2693152-T3 |
| titleOfInvention | Pyrimido-diazepinone compound |
| abstract | A compound represented by the general formula (I), or a pharmaceutically acceptable salt thereof ** Formula ** in which Ra represents a hydrogen, halogen, hydroxy, or alkoxy atom in which the alkyl moiety is linear or branched and has 1 to 10 carbon atoms, R1 and R2 may be the same or different, and each represents an optionally substituted hydrogen, linear or branched alkyl atom having 1 to 10 carbon or cycloalkyl atoms, or R1 and R2 are combine together with the adjacent nitrogen atom thereto to form a nitrogen-containing heterocyclic group, and Z represents a bicyclic heterocyclic group in which two optionally substituted six-membered rings fuse together, wherein; linear or branched alkyl having 1 to carbon atoms is optionally substituted with 1 to 3 substituents, which may be the same or different, selected from the group consisting of halogen, hydroxy, sulfanyl, nitro, cyano, carboxy, carbamoyl, cycloalkyl C3-8, C6-14 aryl, an aliphatic heterocyclic group, an aromatic heterocyclic group, C1-10 alkoxy, C3-8 cycloalkoxy, C6-14 aryloxy, C7-16 aralkyloxy, C2-11 alkanoyloxy, C7-15 aroyloxy, alkylsulfanyl C1-10, -NRXRY, C2-11 alkanoyl, C7-15 aroyl, C1-10 alkoxycarbonyl, C6-14 aryloxycarbonyl, C1-10 alkylcarbamoyl or C1-10 dialkylcarbamoyl, wherein the two C1-10 alkyl radicals of C1 dialkylcarbamoyl -10 can be the same or different; Z is optionally substituted with 1 to 3 substituents, which may be the same or different, selected from the group consisting of oxo, halogen, hydroxyl, sulfanyl, nitro, cyano, carboxy, carbamoyl, C1-10 alkyl, C3-8 cycloalkyl, aryl C6-14, an aliphatic heterocyclic group, an aromatic heterocyclic group, C1-10 alkoxy, C3-8 cycloalkoxy, C6-14 aryloxy, C7-16 aralkyloxy, C2-11 alkanoyloxy, C7-15 alkyloxyloxy, - NRXbRYb, C2-11 alkanoyl, C7-15 aroyl, C1-10 alkoxycarbonyl, C6-14 aryloxycarbonyl, C1-10 alkylcarbamoyl, or C1-10 dialkylcarbamoyl; RX, RY, RXb and RYb may be the same or different, and are selected from the group consisting of hydrogen, C1-10 alkyl, C3-8 cycloalkyl, C6-14 aryl, an aromatic heterocyclic group, C7-16 aralkyl, C2 alkanoyl -11, C7-15 aroyl, C1-10 alkoxycarbonyl, or C7-16 aralkyloxycarbonyl; wherein C1-10alkyl, C1-10alkyl moiety of C1-10alkoxy, C2-11alkanoyloxy, C1-10alkylsulfanyl, C2-11alkanoyl, C1-10alkoxycarbonyl, C1-10alkylcarbamoyl and C1-10 dialkylcarbamoyl are optionally further substituted by 1 to 3 substituents, which may be the same or different, selected from the group consisting of halogen, hydroxy, sulfanyl, nitro, cyano, carboxy, carbamoyl, C3-8 cycloalkyl, C6-14 aryl, a heterocyclic group aliphatic, an aromatic heterocyclic group, C1-10 alkoxy, C3-8 cycloalkoxy, C6-14 aryloxy, C7-16 aralkyloxy, C2-11 alkanoyloxy, C7-15 aroyloxy, C1-10 alkylsulfanyl, -NRXRY, C2-11 alkanoyl, C7-15 aroyl, C1-10 alkoxycarbonyl, C6-14 aryloxycarbonyl, C1-10 alkylcarbamoyl or C1-10 dialkylcarbamoyl, wherein the two C1-10 alkyl residues of the C1-10 dialkylcarbamoyl may be the same or different. |
| priorityDate | 2011-05-10-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
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