http://rdf.ncbi.nlm.nih.gov/pubchem/patent/ES-2692206-T3
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_b5095f60dee8e6d7c3faa7cca7b58c08 |
| classificationCPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K2039-5156 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K2035-124 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K35-12 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K39-0005 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K38-1774 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P35-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K39-3955 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K35-12 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P35-00 |
| filingDate | 2015-11-25-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 2018-11-30-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_d69d31f7fd2ddc5a8e87b7ed9105b421 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_041d454e5c29378a429a3b68d4f22515 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_e64aa88aec8372d256e485421072c2f2 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_1c5115ac793e5bd691dfd2c5a499f559 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_d13c658d89eafdc1b826a027d4782a74 |
| publicationDate | 2018-11-30-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | ES-2692206-T3 |
| titleOfInvention | Combined immunotherapy of antigen and hematopoietic recognition receptors for the treatment of diseases |
| abstract | A combination of compositions for use in immunotherapy to reduce the side effects of an antigen recognition receptor expressed on the cell membrane of immune effector cells against antigen-expressing non-target cells in an individual, comprising a) said antigen recognition receptor. antigen expressed on the cell membrane of immune effector cells wherein said antigen recognition receptor specifically recognizes an antigen on target cells in said individual; b) hematopoietic cells resistant to the recognition of said antigen by said antigen recognition receptor, wherein said hematopoietic cells have a deviation in said antigen, and where said antigen has said deviation i) has at least one splice variant within of the extracellular domain of said antigen suitable for generating different epitopes for antigen binding domains, or ii) has at least one natural polymorphic form within the extracellular domain of said antigen suitable for generating different epitopes for antigen binding domains; or iii) it is modified to a non-natural polymorphic form within the extracellular domain of said antigen suitable to generate different epitopes for antigen-binding domains, where said non-natural polymorphic form does not alter or affect the natural function of said antigen in cells ; or iv) is eliminated without altering or affecting the natural function of the hematopoietic cell, wherein said antigen is expressed in target cells in said individual and at least in one type of hematopoietic cell of said individual. |
| priorityDate | 2014-11-26-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 352.