http://rdf.ncbi.nlm.nih.gov/pubchem/patent/ES-2692095-T3

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filingDate 2014-05-14-04:00^^<http://www.w3.org/2001/XMLSchema#date>
grantDate 2018-11-30-04:00^^<http://www.w3.org/2001/XMLSchema#date>
inventor http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_aa9b0dc896b0c130d0b7227130b7c036
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publicationDate 2018-11-30-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber ES-2692095-T3
titleOfInvention High-dose imatinib tablets
abstract Oral immediate release pharmaceutical composition consisting of imatinib mesylate in an amount equivalent to 600 mg of imatinib in free base form and at least one pharmaceutically acceptable excipient, where the composition is in the form of a film-coated tablet that comprises 95% to 99% by weight of the mesylate salt of imatinib based on the total weight of the film-coated tablet in which the pharmaceutically acceptable excipients comprised in the core of the tablet are selected from the group consisting of diluents, glidants, lubricants , and their combinations, where: The diluents are selected from the group consisting of lactose, calcium carbonate, calcium sulfate, sugar, dextrates, dextrin, dextrose, dibasic calcium phosphate, kaolin, magnesium carbonate, magnesium oxide, maltodextrin , mannitol, polymethacrylates, potassium chloride, sodium chloride, sorbitol, talc and their combinations; glidants are selected from the group consisting of magnesium trisilicate, talc, and combinations thereof; and lubricants are selected from the group consisting of magnesium stearate, calcium stearate, glyceryl monostearate, glyceryl palmitostearate, hydrogenated castor oil, hydrogenated vegetable oil, mineral oil, polyethylene glycol, sodium benzoate, sodium lauryl sulfate, sodium stearyl fumarate, stearic acid, talc, zinc stearate, and combinations thereof.
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type http://data.epo.org/linked-data/def/patent/Publication

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