http://rdf.ncbi.nlm.nih.gov/pubchem/patent/ES-2690128-T3

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publicationDate 2018-11-19-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber ES-2690128-T3
titleOfInvention X-ray contrast agent purification
abstract A method for the purification of a crude non-ionic iodinated dimeric X-ray contrast agent product, comprising the step of: i) passing a solution of the crude product through a membrane (M1) such that impurities of monomeric compounds and salts cross the membrane (permeate, P1) and the nonionic iodinated dimeric X-ray contrast agent passes over the membrane (retained, R1), providing a purified dimeric X-ray contrast agent having a purity of at least 98%; where the impurities of monomeric compounds are compounds that have a molecular weight between 435 and 900 Da, and where M1 has a cut size between 950 and 1,200 Da.
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