abstract |
A conjugate of formula ** Formula ** ConjA: ** Formula ** ConjB: ** Formula ** ConjC: ** Formula ** ConjD: ** Formula ** or ConjE ** Formula ** where Ab is an antibody that binds to PSMA, the antibody comprising a VH domain having the sequence according to any one of SEQ ID NO 1, 3, 5, 7, 8, 9 or 10, further comprising, optionally, a VL domain having the sequence according to any one of SEQ ID NO. 2, 4, 6, 11, 12, 13, 14, 15, 16, 5, 17 or 18; and wherein the drug load (p) of the drugs (D) to the antibody (Ab) is an integer from 1 to about 8. |