abstract |
A polypeptide having cellobiohydrolase activity, wherein the polypeptide comprises an amino acid sequence having a sequence identity of at least 90% with SEQ ID NO: 5 wherein the polypeptide is modified at one or more positions selected from the group consisting in Q1, Q2, T7, A8, N10, Q28, E65, S86, D181, E183, D202, P224, S311, N318, T335, D346, Q349, T392, T393 and Y422, and where the polypeptide maintains 50% of its maximum substrate transformation capacity when the transformation is carried out for 60 minutes at a temperature of 62 ° C or higher. |