http://rdf.ncbi.nlm.nih.gov/pubchem/patent/ES-2687826-T3
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_bbfc0ffb1f1d58b3abc04959050a61fc |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-4412 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P31-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D211-90 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D213-87 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D213-86 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D211-90 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P31-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-4412 |
| filingDate | 2015-07-29-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 2018-10-29-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_7696d093c7343b621ca1440d5631473f http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_3437782bb5c3d711925e3734c02a104f |
| publicationDate | 2018-10-29-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | ES-2687826-T3 |
| titleOfInvention | Arylhydrazides containing a fraction of 2-pyridone as selective antibacterial agents |
| abstract | A compound of the formula (I): ** Formula ** a pharmaceutically acceptable salt, solvate, isotope, polymorph or tautomer thereof, wherein A is a radical selected from A1, A2, A3 and A4; ** Formula ** A1 is ** Formula ** A2 is ** Formula ** A3 is ** Formula ** A4 is ** Formula ** R1 and R2 are independently selected from hydrogen, C1-4alkyl, haloC1-4alkyl, hydroxyC1-4alkyl and C1-4alkoxyC1-4alkyl; R3, R4, R5, R6 and R7 are independently selected from hydrogen, -OH, halogen, C1-6alkyl, C3-6cycloalkyl, -NR12R13, -N (R12) COR13, -N (R12) SO2R13, haloC1-6alkyl, hydroxyC1 -6alkyl, C1-4alkoxy, C1-4alkoxyC1-6alkyl, -COOR12, -CN, -CONR12R13, -SO2-C1-4alkyl, -SO2-O-C1-4alkyl and -SO2-NR12R13; R8 is selected from C1-6alkyl, C2-6alkenyl, C2-6alkynyl, haloC1-6alkyl, hydroxyC1-4alkyl, C1-4alkoxy, C1-4alkoxyC1-4alkyl, C3-6cycloalkylC1-4alkyl, PhC1-4alkyl and -C1Ralkyl-CON13 ; R9, R10 and R11 are independently selected from hydrogen, C1-6alkyl, C3-6cycloalkylC0-4alkyl, -NR12R13, -N (R12) COR13, -N (R12) SO2R13, haloC1-6alkyl, hydroxyC1-6alkyl, C1-4alkoxy, C1-4alkoxyC1-6alkyl, -COOR12, -CN, -CONR12R13, -SO2-C1-4alkyl, -SO2-O-C1-4alkyl and -SO2-NR12R13; and each R12 and R13 are independently selected from hydrogen and C1-4alkyl; wherein the term C3-6-cycloalkyl, as a group or as part of a group, means a monocyclic, non-aromatic hydrocarbon ring, comprising from 3 to 6 carbon atoms, which may be optionally substituted by one or more substituents independently selected from C1-4alkyl, C1-4alkoxy and halogen; and where the term Ph means a phenyl group that may be optionally substituted by one or more substituents independently selected from C1-4alkyl, C1-4alkoxy and halogen provided the following products are excluded: 1-methyl-6-oxo-1 acid , 6-dihydro-pyridine-2-carboxylic acid N'-phenylhydrazide, 1-benzyl-2-oxo-1,2-dihydro-pyridine-3-carboxylic acid N '- (2- (trifluoromethyl) phenyl) -hydrazide, acid 1-Benzyl-4,6-dimethyl-2-oxo-1,2-dihydro-pyridine-3-carboxylic N'-phenyl-hydrazide, 1-methyl-2-oxo-1,2-dihydro-pyridine-4 -N '- (2,4,6-trichlorophenyl) -hydrazide, 1 - ((3-methylphenyl) methyl) -2-oxo-1,2-dihydro-pyridine-3-carboxylic acid N' - (3- (trifluoromethyl) phenyl) -hydrazide and 1 - ((2-chlorophenyl) methyl) -6-oxo-1,6-dihydro-pyridine-3-carboxylic acid N'-phenyl-N'-methyl-hydrazide. |
| priorityDate | 2014-07-30-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
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