| abstract |
A compound represented by the following formula: ** Formula ** wherein the P ring is pyridine; W is methylene; ring A is piperidine, azetidine or pyrrolidine; Ring B is (1) a benzene ring optionally substituted with 1 to 4 substituents selected from: a halogen atom; a C3-10 cycloalkyl group; a C1-6 alkoxy group; and a C6-14 aryl group optionally substituted with 1 to 3 halogen atoms, or (2) pyridine, indole or pyrazole, each optionally substituted with 1 to 3 substituents selected from: a C1-6 alkyl group; a C3-10 cycloalkyl group; a C1-6 alkoxy group; and a C6-14 aryl group optionally substituted with 1 to 3 halogen atoms, R1 is a hydrogen atom or COOH; R2 is a hydrogen atom, a C1-6 alkyl group optionally substituted by a C1-6 alkoxy group, a C3-10 cycloalkyl group or COOH; and one of R1 and R2 is COOH, and each of R3, R4, R5 and R6 is a hydrogen atom, or a pharmacologically acceptable salt thereof. |