http://rdf.ncbi.nlm.nih.gov/pubchem/patent/ES-2686929-T3
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_e13cf25eb1bef6199475314477618b46 |
| classificationCPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07C2602-20 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07B2200-07 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07C45-85 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07C227-30 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07B57-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07C45-80 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07C227-12 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C227-30 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07B57-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07B61-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C227-12 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C49-627 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C45-85 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C229-32 |
| filingDate | 2012-12-13-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 2018-10-22-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_4e4f20e207caf9a584c4dcf73a937bc6 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_6ae9dd3d4af1e1e81486eba54baf4508 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_fbe202dddadd958c9fd2023740b50975 |
| publicationDate | 2018-10-22-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | ES-2686929-T3 |
| titleOfInvention | Optical resolution procedure for bicyclic compound using asymmetric catalyst |
| abstract | A process for the production of a compound represented by the general formula (I): ** Formula ** comprising the process (1) reacting a racemic mixture of the compound represented by the general formula (I) and a compound represented by the general formula (II) with a compound represented by the general formula (III) in the presence of an optically active amine and a solvent to convert the compound represented by the general formula (II) into a compound represented by the general formula (II ') and a compound represented by the general formula (II "): ** Formula ** in which the optically active amine is any amine selected from the following group: ** Formula ** in which the symbols represent substituents defined as follows: Me : a methyl group, Ph: a phenyl group, Bn: a benzyl group, Et: an ethyl group, iPr: an isopropyl group, tBu: a tertiary butyl group, and Tf: a trifluoromethanesulfonyl group, and the solvent is any solvent s selected from the following group: acetonitrile, 2-15 propanol, tetrahydrofuran, 1,2-dimethoxyethane, dimethylacetamide, dimethylformamide, N-methyl-2-pyrrolidone, 1,3-dimethyl-2-imidazolidinone, and dimethylsulfoxide, then ** Formula * * (2) separate the compound represented by the general formula (I) from the compound represented by the general formula (II ') and the compound represented by the general formula (II ") to produce the compound represented by the general formula (I) : ** Formula ** in which the substituents are defined as follows: R1: a hydrogen atom or a C1-C6 alkyl group; and R2 and R3 are the same or different and each is a group selected from a hydrogen atom, a halogen atom, a nitro group, and a carboxy group. |
| priorityDate | 2011-12-15-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 101.