http://rdf.ncbi.nlm.nih.gov/pubchem/patent/ES-2683631-T3

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filingDate 2010-02-26-04:00^^<http://www.w3.org/2001/XMLSchema#date>
grantDate 2018-09-27-04:00^^<http://www.w3.org/2001/XMLSchema#date>
inventor http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_728b9bf37a8643c4fbeea5f5ed731d33
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publicationDate 2018-09-27-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber ES-2683631-T3
titleOfInvention Diagnostic improvement in liver fibrosis or cirrhosis
abstract A procedure to diagnose the presence and / or severity of a liver pathology and / or to monitor the effectiveness of a curative treatment against a liver pathology in an individual, which leads to a score that comprises: a) performing, from the sample of an individual's blood, at least one FibroMeter test, b) perform at least one Fibroscan test in order to collect at least one series of data on the Liver Stiffness Assessment (LSE), and c) combine at least said test for FibroMeter and at least one series of LSE data in a mathematical binary logistic regression function of formula p> = 1 / (1 + exp (- a0 - a1 x1 - a2 x2)), where a0 is a constant, x1 and x2 they are independent variables that correspond to the value of FibroMeter obtained in stage a) and the value of Fibroscan obtained in stage b), and a1 and a2 are coefficients associated with said value of FibroMeter and said value of Fibroscan, thus giving the result of a new score ón for the diagnosis of the presence and / or severity of a liver pathology and / or the supervision of the effectiveness of a curative treatment against a liver pathology in an individual, where said liver pathology is a significant portoseptal fibrosis, severe portoseptal fibrosis, fibrosis centrolobular, cirrhosis, persinusoidal fibrosis, not having the fibrosis cause in alcohol consumption.
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