| abstract |
A drug and antibody conjugate comprising an anti-191P4D12 antibody or an antigen binding fragment thereof, wherein the antibody or fragment thereof comprises a heavy chain variable region consisting of amino acid residue 20 to amino acid residue. 136 of SEQ ID NO: 7 and a variable region of the light chain consisting of amino acid residue 23 to amino acid residue 130 of SEQ ID NO: 8, and wherein the antibody or fragment thereof is conjugated to monomethyl auristatin E (MMAE). |