http://rdf.ncbi.nlm.nih.gov/pubchem/patent/ES-267817-A1
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_f07293d4b34d8372fb0775181fef9d23 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D- |
| filingDate | 1961-05-31-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationDate | 1962-02-16-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | ES-267817-A1 |
| titleOfInvention | PROCEDURE FOR OBTAINING NEW 3-PHENYL-PYRROLIDINES AND THEIR SALTS |
| abstract | Procedure for obtaining new 3-phenyl-pyrrolidines of the general formula ** (See formula) ** and of their salts, wherein R1-R6 represent hydrogen or a lower alkyl, and Z hydrogen, an aryl, furyl or thionyl residue, optionally mono- or pluri- substituted with halogen, an alkyl, alkoxy, hydroxyl or methylenedioxy group, or a cycloalkyl radical optionally containing an endomethylene group, one of the substituents Z having to be a phenyl radical substituted with an oxygenated radical, characterized by being reduced catalytically or electrocatalytically a) 1,4-Nitrocarbonyl compounds of the formula ** (See formula) ** where R1 - R5 and Z have the indicated meaning, b) 1-cyano-3-oxo compounds of the formula ** (See formula) ** where R2 - R4 and Z have the indicated meaning, c) succinic acid dinitriles of the formula ** (See formula) ** d) 1-nitro- and respectively 1-amino-4-nitriles of the formula ** (See formula) ** where X represents an amino or nitro group and R1 - R4 and Z have the meaning indicated above, or transform e) 1,4-butylene dihalides of the formula ** (See formula) ** where Z and R1-R6 have the indicated meaning and Hal represents chlorine, bromine or iodine, with ammonia or benzylamine, and the benzyl residue is eventually removed by hydrogenation, or transform f) Bitulene 1,4-diols of the formula ** (See formula) ** and, respectively, their diesters, with R1-R5 and Z having the indicated meaning, with ammonia or benzylamine, and possibly removing the benzyl residue by hydrogenation, reducing it catalytically or electrolytically. g) alpha-pyrrolidone de la foam ** (See formula) ** where R3 - R6 and Z have the indicated meaning, with LiAlH4, boron hydrides, catalytic or electrolytic reduction of succinic acid of the formula ** (See formula) ** where R3, R4 and Z have the indicated meaning, with LiAlH4, catalytically reduce i) pyrrolines of the formula ** (See formula) ** where R2- R6 and Z have the indicated meaning, and the reaction products are optionally converted into salts. (Machine-translation by Google Translate, not legally binding) |
| priorityDate | 1961-05-31-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 38.