| abstract |
CD2 polypeptide for use in a method for reducing pathological angiogenesis in an individual, the method comprising: administering to an individual an effective dose of a variant of domain one of the human or mouse polypeptide, where administration provides the reduction of pathological angiogenesis in the individual, and wherein the polypeptide is selected from the group consisting of Sequence No. Id. 1, Sequence No. Id. 2, Sequence No. Id. 3, Sequence No. Id. 4, Sequence No. Id. 5, Sequence No. Id. 6, Sequence No. Id. 7, Sequence No. Id. 8, Sequence No. Id. 9, Sequence No. Id. 10, and Sequence No. Id. 11. |