| abstract |
Compound of formula I: ** Formula ** or a pharmaceutically acceptable salt thereof, wherein: W is O, N-H, N- (C1-C10 alkyl) or S; each X is independently CH or N; R1 is an optionally substituted, saturated or unsaturated 5 to 7 membered heterocycle containing at least 1 heteroatom selected from N or O; R2 is LY; each L is a direct bond, C1-C10 alkylene, C2-C10 alkenylene, C2-C10 alkynylene, Y is an optionally substituted non-aromatic 5-12 membered heterocycle, fused, bridged or spirocyclic containing up to 4 heteroatoms selected from N u OR; and each R3 is independently H, C1-C10 alkyl, halogen, fluoro-C1-C10 alkyl, O-C1-C10 alkyl, NH C1-C10 alkyl, S-C1-C10 alkyl, O-fluoro-C1-C10 alkyl, NH -acrylic, NH-C (O) -NH-C1-C10 alkyl, C (O) -NH C1-C10 alkyl, aryl or heteroaryl. |