abstract |
A long-acting human growth hormone conjugate formulation, comprising a pharmaceutically effective amount of the long-acting human growth hormone conjugate in which the human growth hormone is bound to an immunoglobulin Fc region, and a stabilizer albumin-free, said stabilizer comprising a buffer of pH 5.0 to about 6.0, a sugar alcohol, a non-ionic surfactant and sodium chloride, wherein said non-ionic surfactant is used in an amount of from 0.001 to 0.05% (w / v) based on the total volume of the formulation. |