http://rdf.ncbi.nlm.nih.gov/pubchem/patent/ES-2672806-T3
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_0c4940f75f1bdd2c4fc2eb7addb705f8 |
| classificationCPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61L2430-02 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P19-08 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61L27-46 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61L27-46 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61L27-54 |
| filingDate | 2010-04-11-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 2018-06-18-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_a8be7bc00800fc7445a6e4033781bcc3 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_f50394b92e9583fb1d476c067a6c375b |
| publicationDate | 2018-06-18-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | ES-2672806-T3 |
| titleOfInvention | Bone graft and biocomposite material |
| abstract | A bone graft material for the treatment of bone defects and bone neogenesis, which is a material composed of a biodegradable polymer and beta tricalcium phosphate granules, obtained by the steps of: providing an osteoinductive mixture, which is a dispersion or solution to base of an organic compound having at least one basic nitrogen-containing non-reactive group, having a pKa value of 2 to 14, organic compound which is both a dispersing agent and a plasticizer of the biodegradable polymer or copolymer and which can form a salt with a protein having a pKI of 4.0, and a physiologically effective amount of active recombinant human BSP obtained under non-denaturing conditions, where the recombinant human BSP is present in said osteoinductive mixture in the form of an affinity salt or complex reduced by calcium, hydroxyapatite and complement factor H compared to normal human BSP present tea in human serum, and, optionally, a pharmaceutically acceptable carrier or excipient; provide an osteoconductive mixture based on tricalcium diphosphate (Ca3 (PO4) 2) granules in the form of a beta crystal, granules that are coated with a biodegradable polymer or copolymer and, optionally, a pharmaceutically acceptable carrier or excipient, osteoconductive mixture that is moldable and conformable, and quickly hardens in situ when placed by surgery or prosthetic dentistry; and combining said osteoinductive and osteoconductive mixtures to obtain a bone graft material that promotes bone repair and the healing of damaged and diseased tissues and injuries. |
| priorityDate | 2009-07-03-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 393.