| abstract |
A pharmaceutical composition comprising a polynucleotide and a compound of the formula: ** Formula ** or a salt thereof, in which: connector B is selected from the group consisting of carbon chains of 1 to 30 carbon atoms, chains carbon containing heteroatoms of 1 to 30 atoms and carbon chains and carbon chains containing heteroatoms with at least one substituent selected from the group consisting of branched and unbranched alkyl groups, branched and unbranched alkenyl, branched and unbranched alkynyl , amino, alkylamino, dialkylamino, trialkylamino, aryl, ureido, heterocyclic, aromatic heterocyclic, cyclic, aromatic cyclic, halogen, hydroxyl, alkoxy, cyano, amide, carbamaoyl, carboxylic acid, ester, carbonyl, carbonyldioxyl, alkylthioether and thiol; R1 is selected from the group consisting of branched and unbranched alkyl, branched and unbranched alkenyl, branched and unbranched alkynyl, aryl, carbamoyl, carboxylic ester, amide, a substituted alkanoyl, cyclic, aromatic cyclic, heterocyclic and aromatic heterocyclic groups , wherein each of which may be substituted with at least one substituent selected from the group consisting of branched and unbranched alkyl, branched and unbranched alkenyl, branched and unbranched alkynyl, amino, alkylamino, dialkylamino, trialkylamino, aryl groups , ureido, heterocyclic, aromatic heterocyclic, cyclic, aromatic cyclic, halogen, hydroxyl, alkoxy, cyano, amide, carbamoyl, carboxylic acid, ester, carbonyl, carbonyldioxyl, alkylthioether and thiohydroxy; R2, R3, R4, R5, R6 and R7 are each hydrogen; and n is an integer between 5 and 10,000; optionally wherein the pharmaceutical composition further comprises a pharmaceutically acceptable carrier or a pharmaceutically acceptable excipient. |