| abstract |
A non-aqueous pharmaceutical composition for dermal use, said composition comprising a first pharmacologically active component A consisting of at least one vitamin D or vitamin D analogue and a second pharmacologically active component B consisting of at least one corticosteroid, characterized by that the difference between the optimum stability pH of said first component A and the optimum stability pH of said second component B is at least 1; and at least one solvent component C selected from the group consisting of: (i) compounds of the general formula H (OCH2C (R1) H) xOR2 (II) in which x is in a range of 2-60, R1 in each of the units x is CH3, and R2 is C1-20 alkyl or straight or branched chain benzoyl. |