http://rdf.ncbi.nlm.nih.gov/pubchem/patent/ES-2671550-T3
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_bb75b0b19820e3833ebdcb31603b242b |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P43-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P31-16 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P31-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D471-14 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D471-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-53 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D498-14 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D487-14 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D487-20 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-53 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-5383 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-5377 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-4985 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D498-14 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D471-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D471-14 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P43-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P31-16 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-553 |
| filingDate | 2010-06-14-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 2018-06-07-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_8b7b819668b72d56ec96f6dbac1a4c6b http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_9f52521ac29787cf7e1223ae85499610 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_14115e6208558c57f89577bd98c7b1dc http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_acddc374b84876a17d9cc71512b0977f http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_027bcaf3aea39fc44d770774828405a1 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_3bf23db9ebbf8510f81cc3d5f804e7c2 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_1bac1c5cb09665d0bd3e90792ceb00d0 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_484536f58313afe34946f0144567f589 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_0802e3e92079ebd3b83741b568ee6d6f http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_c357ff83fd94791a40877781dacf77fa |
| publicationDate | 2018-06-07-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | ES-2671550-T3 |
| titleOfInvention | Polycyclic substituted carbamoylpyridone derivative |
| abstract | A compound represented by formula (I), a pharmaceutically acceptable salt or a solvate thereof, for use in the treatment of and / or the prevention of an infectious influenza disease: ** Formula ** R1 is hydrogen, halogen , hydroxy, carboxy, cyano, formyl, lower alkyl optionally substituted with a group of substituents A, lower alkenyl optionally substituted with a group of substituents A, lower alkynyl optionally substituted with a group of substituents A, lower alkyloxy optionally substituted with a group of substituents A, lower alkenyloxy optionally substituted with a group of substituents A, lower alkylcarbonyl optionally substituted with a group of substituents A, lower alkyloxycarbonyl optionally substituted with a group of substituents A, carbocyclic group optionally substituted with a group of substituents A, carboxy lower alkyl optionally substituted with a group of substituents A, carbo cyclocarbonyl optionally substituted with a group of substituents A, carbocyclooxy optionally substituted with a group of substituents A, carbocyclooxycarbonyl optionally substituted with a group of substituents A, heterocyclic group optionally substituted with a group of substituents A, lower alkyl heterocycle optionally substituted with a group of A substituents, heterocyclocarbonyl optionally substituted with a group of substituents A, heterocyclooxy optionally substituted with a group of substituents A, heterocyclooxycarbonyl optionally substituted with a group of substituents A, -ZN (RX1) (RX2), -ZN (RX3) -SO2- (RX4), -ZC (> = O) -N (RX5) -SO2- (RX6), -ZN (RX7) -C (> = O) -RX8, -ZC (> = O) -N (RX9) (RX10), -ZS-RX11, -Z-SO2-RX12, -ZS (> = O) -RX13, -ZN (RX14) -C (> = O) -O-RX15, -ZN (RX16) -C (> = O) -N (RX17) (RX18), -ZC (> = O) -N (RX19) -C (> = O) -N (RX20) (RX21) or -ZN (RX22) -C ( > = O) -C (> = O) -RX23 (where RX1, RX2, RX3, RX5, RX7, RX8, RX9, RX10, RX11, RX14, RX15, RX16, RX17, RX18, RX19 , RX20, RX21, RX22, and RX23 are each independently selected from a group of substituents consisting of hydrogen, lower alkyl optionally substituted with a group of substituents A, lower alkenyl optionally substituted with a group of substituents A, lower alkynyl optionally substituted with a group of substituents A, carbocyclic group optionally substituted with group of substituents A, heterocyclic group optionally substituted with group of substituents A, lower alkyl carbocycle optionally substituted with a group of substituents A, and lower alkyl heterocycle optionally substituted with a group of substituents A, RX4, RX6, RX12 and RX13 are each independently selected from a group of substituents consisting of lower alkyl optionally substituted with a group of substituents A, lower alkenyl optionally substituted with a group of substituents A, optionally substituted lower alkynyl c With a group of substituents A, carbocyclic group optionally substituted with a group of substituents A, heterocyclic group optionally substituted with a group of substituents A, lower alkyl carbocycle optionally substituted with a group of substituents A, and lower alkyl heterocycle optionally substituted with a group of substituents A, RX1 and RX2, RX9 and RX10, RX17 and RX18, and RX20 and RX21 can each be taken together with an adjacent atom to form heterocycle, and Z is a linear or branched lower alkylene or bond); R2 is hydrogen, halogen, hydroxy, carboxy, cyano, formyl, lower alkyl optionally substituted with a group of substituents A, lower alkenyl optionally substituted with a group of substituents A, lower alkynyl optionally substituted with a group of substituents A, optionally lower alkyloxy substituted with a group of substituents A, lower alkenyloxy optionally substituted with a group of substituents A, lower alkylcarbonyl optionally substituted with a group of substituents A, lower alkyloxycarbonyl optionally substituted with a group of substituents A, carbocyclic group optionally substituted with a group of substituents A, carboxy lower alkyl optionally substituted with a group of substituents A, carbocyclocarbonyl optionally substituted with a group of substituents A, carbocyclooxy optionally substituted with a group of substituents A, carbocyclooxycarbonyl optionally substituted 5 with a group of their substituents A, heterocyclic group optionally substituted with a group of substituents A, lower alkyl heterocycle optionally substituted with a group of substituents A, heterocyclocarbonyl optionally substituted with a group of substituents A, heterocyclooxy optionally substituted with a group of substituents A, heterocyclooxycarbonyl optionally substituted with a group of substituents A, -ZN (RY1) -SO2-RY2, -ZN (RY3) -C (> = O) -RY4, -ZN (RY5) -C (> = O) -O-RY6, -ZC (> = O) -N (RY7) (RY8), -ZN (RY9) (RY10) or -Z-SO2-RY11 (where RY1, RY3, RY4, RY5, RY6, RY7, RY8, RY9 and RY10 each is independently selected from a group of substituents consisting of hydrogen, lower alkyl optionally substituted with a group of substituents A, lower alkenyl optionally substituted with a group of substituents A, lower alkynyl optionally substituted with a group of substituents A, carbocyclic group optionally substituted with a group of substituents A, heterocyclic group optionally substituted with a group of substituents A, carboxy lower alkyl optionally substituted with a group of substituents A and lower alkyl heterocycle optionally substituted with a group of substituents A, RY2 and RY11 are each independently selected from a group of substituents consisting in lower alkyl optionally substituted with a group of substituents A, lower alkenyl optionally substituted with a group of substituents A, lower alkynyl optionally substituted with a group of substituents A, carbocyclic group optionally substituted with a group of substituents A, heterocyclic group optionally substituted with a group of substituents A, lower alkyl carbocycle optionally substituted with a group of substituents A, and lower alkyl heterocycle optionally substituted with a group of substituents A, RY7 and RY8, and RY9 and RY10 can be taken together with an adjacent atom to form an h heterocycle and Z is a linear or branched bond or lower alkylene); R3 is hydrogen, hydroxy, carboxy, cyano, formyl, lower alkyl optionally substituted with a group of substituents A, lower alkenyl optionally substituted with a group of substituents A, lower alkynyl optionally substituted with a group of substituents A, lower alkyloxy optionally substituted with a group of substituents A, lower alkenyloxy optionally substituted with a group of substituents A, lower alkylcarbonyl optionally substituted with a group of substituents A, lower alkyloxycarbonyl optionally substituted with a group of substituents A, carbocyclic group optionally substituted with a group of substituents A, carboxy lower alkyl optionally substituted with a group of substituents A, carbocyclooxy lower alkyl optionally substituted with a group of substituents A, carbocyclocarbonyl optionally substituted with a group of substituents A, carbocyclooxy optionally substituted with a group of substituents entities A, carbocyclooxycarbonyl optionally substituted with a group of substituents A, heterocyclic group optionally substituted with a group of substituents A, lower alkyl heterocycle optionally substituted with a group of substituents A, heterocyclooxy lower alkyl optionally substituted with a group of substituents A, heterocyclocarbonyl optionally substituted with one group of substituents A, heterocyclooxy optionally substituted with one group of substituents A, heterocyclooxycarbonyl optionally substituted with one group of substituents A, -ZN (RZ1) -SO2-RZ2, -ZN (RZ3) -C (> = O) -RZ4, -ZN (RZ5) -C (> = O) -O-RZ6, -ZC (> = O) -N (RZ7) (RZ8), -ZN (RZ9) (RZ10), -Z-SO2- RZ11 or -ZN (RZ12) -OC (> = O) -RZ13 (where RZ1, RZ3, RZ4, RZ5, RZ6, RZ7, RZ8, RZ9, RZ10, RZ12 and RZ13 are each independently selected from a group of substituents consisting of hydrogen, lower alkyl optionally substituted with a group of substituents A, lower alkenyl optionallym entity substituted with a group of substituents A, lower alkynyl optionally substituted with a group of substituents A, carbocyclic group optionally substituted with a group of substituents A, heterocyclic group optionally substituted with a group of substituents A, carboxy lower alkyl optionally substituted with a group of substituents A and heterocyclo lower alkyl optionally substituted with a group of substituents A, RZ2 and RZ11 are each independently selected from a group of substituents consisting of lower alkyl optionally substituted with a group of substituents A, lower alkenyl optionally substituted with a group of substituents A, lower alkynyl optionally substituted with a group of substituents A, carbocyclic group optionally substituted with a group of substituents A, heterocyclic group optionally substituted with a group of substituents A, lower alkyl carbocycle optionally substituted co n a group of substituents A and lower alkyl heterocycle optionally substituted with a group of substituents A, RZ7 and RZ8, and RZ9 and RZ10 can each be taken together with an adjacent atom to form a heterocycle and Z is a linear lower alkylene or bond or branched) and; a) A1 or A2 is CR5R6 and the other is NR7, or b) A1 is CR8R9 and A2 is CR10R11, |
| priorityDate | 2009-06-15-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
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Total number of triples: 363.