abstract |
A pharmaceutical formulation for oral administration to prevent or treat allergic rhinitis or asthma, comprising: (a) a first portion of particles comprising levocetirizine or a pharmaceutically acceptable salt thereof and an organic acid; and (b) a second particle portion comprising montelukast or a pharmaceutically acceptable salt thereof, wherein said first or second particle portions are in the form of a mini-tablet; and said organic acid is selected from the group consisting of citric acid, tartaric acid, succinic acid, ascorbic acid, and a mixture thereof. |