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publicationDate 2018-06-06-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber ES-2671428-T3
titleOfInvention Stable pharmaceutical formulation for oral administration, comprising levocetirizine or a pharmaceutically acceptable salt thereof and montelukast or a pharmaceutically acceptable salt thereof.
abstract A pharmaceutical formulation for oral administration to prevent or treat allergic rhinitis or asthma, comprising: (a) a first portion of particles comprising levocetirizine or a pharmaceutically acceptable salt thereof and an organic acid; and (b) a second particle portion comprising montelukast or a pharmaceutically acceptable salt thereof, wherein said first or second particle portions are in the form of a mini-tablet; and said organic acid is selected from the group consisting of citric acid, tartaric acid, succinic acid, ascorbic acid, and a mixture thereof.
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