| abstract |
Use of a modified yeast strain for the production of compounds, wherein said modified yeast strain belongs to a yeast species capable of producing sophorolipids, characterized in that said modified yeast strain has, compared to the unmodified wild-type strain which is fully capable of producing said sophorolipids, at least one gene encoding an enzyme selected from the group consisting of cytochrome P450 monooxygenase or a glycosyltransferase inactivated through the insertion of an inactivation cassette, wherein said inactivation causes a reduction in its ability to produce said sophorolipids of at least 95%, compared to the total production of sophorolipids per unit time in said unmodified wild-type strain, and wherein said sophorolipids consist of the sugar sophorose bound to a C16 fatty acid, C18, C22 or C24 hydroxylated. |