http://rdf.ncbi.nlm.nih.gov/pubchem/patent/ES-2668555-T3
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_715946dfd122eb9277028d69e0cf56a3 |
| classificationCPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/Y10T436-143333 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q2527-00 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q1-6841 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q1-6832 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q1-6876 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12Q1-68 |
| filingDate | 2009-05-27-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 2018-05-18-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_dfe41121edd0ec95d39ec520a410beb8 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_e057929930b5f0ab7eaf3b30f2da7d8a http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_a9c5102dac5ebf56a3d8f73fa2216a9b |
| publicationDate | 2018-05-18-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | ES-2668555-T3 |
| titleOfInvention | Compositions and methods for the detection of chromosomal aberrations with novel hybridization buffers |
| abstract | In situ hybridization method for determining the presence of a chromosomal aberration in chromosomal DNA, comprising: - providing at least one molecular probe that hybridizes with a nucleic acid sequence associated with chromosomal aberrations, - providing chromosomal DNA, - providing a composition hybridization comprising from 1% (v / v) to 95% (v / v) of at least one polar aprotic solvent having a cyclic base structure, and a hybridization solution, wherein the polar aprotic solvent is selected from the group consisting of: ** (See formula) ** where the hybridization solution comprises at least one additional component selected from the group consisting of: buffering agents, accelerating agents, chelating agents, salts, detergents and blocking agents, and with the proviso that the hybridization composition contains less than 10% formamide, - combining the molecular probe, chromosomal DNA and the hybrid composition Riding for at least a sufficient period of time to hybridize the molecular probe with the target, and - detect the at least one molecular probe, - and determine the presence of chromosomal aberration. |
| priorityDate | 2008-05-27-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 1372.