Predicate |
Object |
assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_a43ef275ae6f6fafc66975041eb60aa7 |
classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N2800-044 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N2333-924 |
classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K9-0019 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-6854 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Y302-01045 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P3-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N9-2402 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N9-2442 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Y302-01014 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K45-06 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K38-47 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-543 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-53 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q1-25 |
classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K38-47 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N33-68 |
filingDate |
2010-07-28-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
grantDate |
2018-05-16-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_5fdd7c6d6a4ba96dc3ed4cebd15ff0c8 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_280545c082c24724c04947c4b9131262 |
publicationDate |
2018-05-16-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber |
ES-2668079-T3 |
titleOfInvention |
Compositions and methods to treat Gaucher's disease |
abstract |
A method of identifying a subject as suitable for treatment with an alternative glucocerebrosidase enzyme, the method comprising: determining whether a neutralizing antibody to a glucocerebrosidase enzyme is present in a sample from a subject who is currently taking or has previously received the glucocerebrosidase enzyme for obtain a measured value of the antibody; comparing the measured value with a standard, where if the measured value is greater than the standard, it is identified that the subject has tested positive for the production of the antibodies; and selecting a subject for the alternative glucocerebrosidase enzyme on the basis that the subject has tested positive for antibody production. |
priorityDate |
2009-07-28-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type |
http://data.epo.org/linked-data/def/patent/Publication |