| abstract |
A composition for use in treatment or prevention of a disorder or disease related to the respiratory mucosa consisting of: a therapeutically effective amount of a mixture of hyaluronic acid consisting of a hyaluronic acid of low average molecular weight (LMWHA) and an acid hyaluronic high molecular weight average (HMWHA), where an average molecular weight (PM) of LMWHA is between 50 kilo Da and 0.5 million Da, and an average PM of HMWHA is between more than 1.5 million Da and 5 million Da, where the average PM of the LMWHA is separated from the average PM of the HMWHA by at least 0.5 million Da, and a mixing ratio of the LMWHA and the HMWHA is in a range of 20:80 to 80 : 20 by weight, and an excipient for formulating the composition in a pharmaceutical form of administration for eye, ear, oral, nose, respiratory tract or topical use, wherein the mucosal-related disorder or disease is allergic rhinitis or bronchitis. |