http://rdf.ncbi.nlm.nih.gov/pubchem/patent/ES-2663614-T3
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_981a37900e6991fb373304ed2ba5a703 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07C225-14 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07C251-08 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07C211-65 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D231-12 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D231-14 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07F5-022 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07F5-02 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07C211-24 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D231-12 |
| filingDate | 2015-03-20-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 2018-04-16-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_8a5f545837ab911f3eb6dab35e57ce1e http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_02dd0df4be77ba478bf148d1d3c8e9bf http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_d799d5c784eea47815cb7de6fd9e4ea3 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_e84b2e54d82718a86f9286e85058ee61 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_d63a8f966150e77dd33e859bce6684ba |
| publicationDate | 2018-04-16-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | ES-2663614-T3 |
| titleOfInvention | Process for preparing 3,5-bis (haloalkyl) pyrazole derivatives from alpha, alpha-dihaloamines and ketimines |
| abstract | Preparation process of 3,5-bis (haloalkyl) pyrazoles of formula (Ia) and (Ib) ** (See formula) ** in which R1 and R3 are each independently selected from C1-C6 haloalkyl; R2 is selected from H, halogen, COOH, (C> = O) OR5, CN and (C> = O) NR6R7; R4 is selected from H, C1-C8 alkyl, CH2COO C1-C8 alkyl, aryl, pyridyl; R5 is selected from C1-C12 alkyl, C3-C8 cycloalkyl, C6-C18 aryl, C7-C19 arylalkyl, and C7-C19 alkylaryl; R6 and R7 are each independently selected from C1-C12 alkyl, C3-C8 cycloalkyl, C6-C18 aryl, C7-C19 arylalkyl and C7-C19 alkylaryl or in which R6 and R7 together with the nitrogen atom to which they are attached they can form a four, five or six membered ring characterized in that in step (A), α, α-dihaloamines of formula (II), ** (See formula) ** in which R1 is as defined above; X is independently selected from F, Cl, or Br, R10 and R11 are each independently selected from C1-C12 alkyl, C3-C8 cycloalkyl, C6-C18 aryl, C7-C19 arylalkyl, and C7-C19 alkylaryl or where R10 and R11 together with the nitrogen atom to which they are attached they can form a five or six membered ring; are reacted with compounds of formula (III), ** (See formula) ** in which R8 is selected from C1-C12 alkyl, C3-C8 cycloalkyl, C6-C18 aryl, C7-C19 arylalkyl and C7 alkylaryl -C19-, OR9; R9 is selected from C1-C12 alkyl, C3-C8 cycloalkyl, C6-C18 aryl, C7-C19 arylalkyl, C7-C19 alkylaryl; R2 and R3 are as defined above; to form the compound of formula (V): (V-1), (V-2), (V-3), (V-4) and (V-5) ** (See formula) ** and because in step (B) in the presence of hydrazine H2N-NHR4 (IV) - R4 being as defined above - a cyclization of (V) is carried out to form (Ia / Ib). |
| priorityDate | 2014-03-24-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
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