| abstract |
Patch comprising a backing layer and a pressure sensitive adhesive layer formed on the backing layer, the pressure sensitive adhesive layer containing: ropinirole and a metal salt produced by a reaction of an acid adduct and ropinirole and a metal ion-containing desalting agent in one mole in equivalents or less with respect to the acid adduct; a free adhesive base of a hydroxyl group and a carboxyl group; and adsorbent that adsorbs a polar solvent contained in the pressure sensitive adhesive layer selected from the group consisting of talc, fumed silica, polyvinylpyrrolidone, propylene glycol, copolymers of aminoalkyl methacrylate, crospovidone, lactic acid and dextrin. |