abstract |
Compound of formula (I) or salt thereof: in the formula, R1 is nitrogen-containing monocyclic aryl or heteroaryl, each of which may be substituted with group (s) selected from the group consisting of halogen, lower alkyl, -O-lower alkyl, halogen-lower alkyl, -O-halogen-lower alkyl, -CN, dimethylamino and cycloalkyl; X is CH, N or C; ** Formula ** is i) a single bond in the case where X is CH or N and ii) a double bond in the case where X is C; Y is a cyclic group described below: ** Formula ** In this case, Y1 is CRh or N, Y2 is CRi or N, provided that Y1 and Y2 are not N at the same time, Ra, Rh, and Ri being equal or different from each other are H or halogen, Rb is H or lower alkyl, Rc is lower alkyl, Y3 is CH or N, Rd and Re which are the same or different from each other are H or lower alkyl, Rf is H or lower alkyl, Y4 is O or S, Y5 is CH or N, Y6 is CH or N, Rg is H or lower alkyl; R2 is H or lower alkyl; R3 and R4 which are the same or different from each other are H, halogen, lower alkyl, -O-lower alkyl, halogen-lower alkyl, -O-halogen-lower alkyl, cycloalkyl, or -CN, or R3 and R4 can form 2 , 2-difluoro-1,3-benzodioxol joining together with the benzene ring to which R3 and R4 are attached; and lower alkyl is a linear or branched alkyl having 1 to 6 carbon atoms. |