| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_cf32b60391b469c41e86c353437f5751 |
| classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K2300-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K9-4866
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K9-4858
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q2600-106
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q2600-16
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q2600-156
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q2600-158
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q2600-172
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K9-1623
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K9-1652 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P25-18
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P25-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q1-6883
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-439
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-44
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-444
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-4748
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K45-06
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P25-28
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K9-2018
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K9-2086
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K9-2054
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K9-2059 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P25-28
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K45-06
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-44
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-4748 |
| filingDate |
2013-12-09-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate |
2018-03-27-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_5eaa511047c24ad091fff13eca722485
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_8cc7d476ae0ae5f733a959b041989992
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_0c154a5890245cbb7077e196fb9468b4
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_889b02f374e2c28aaf476494bb605b13
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_4b1bdc64cda39587c481f4ee2fcf4fc3
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_24dd23bd922de74e38dc6cbfbc70f5a3
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_cbcc55ee47beaeb222df8ecc06ca801d
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_db3d03f956893703605fe35112333c2f
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_4dda41751203f350cc97b8155591b2af |
| publicationDate |
2018-03-27-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
ES-2661050-T3 |
| titleOfInvention |
Biomarker predictive of responsiveness to treatment with activator of nicotinic acetylcholine receptor alpha-7 |
| abstract |
Composition comprising an acetylcholine alpha 7 nicotinic receptor agonist (nAChR) for use in the treatment of cognitive impairments, psychotic and / or neurodegenerative disorders or increasing the cognitive skills of an individual in a selected patient population, where the nAChR agonist alpha-7 is (R) -3- (6-p-tolyl-pyridin-3-yloxy) -1-aza-bicyclo [2.2.2] octane, where the patient population is selected on the basis that they have at least one SNP indicative of human cytochrome P450 1A2 (CYP1A2) and where the selected patients are homozygous for the indicative SNP CYP1A2 rs2069514-A / A indicative (SEQ. ID No. 1) or corresponding indicative or heterozygous CYP1A2 SNP haplotypes for the CYP1A2 SNP rs2069514-A / G indicative or corresponding indicative CYP1A2 SNP haplotypes. |
| priorityDate |
2012-12-11-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |