http://rdf.ncbi.nlm.nih.gov/pubchem/patent/ES-2660642-T3

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grantDate 2018-03-23-04:00^^<http://www.w3.org/2001/XMLSchema#date>
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publicationDate 2018-03-23-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber ES-2660642-T3
titleOfInvention Crystalline forms of dihydropyrimidine derivatives
abstract A crystalline form of the compound of Formula (I): ** (See formula) ** or a tautomer, where the crystalline form is Form B, which has a powder X-ray diffraction pattern (XRPD) comprising peaks expressed in degrees 2θ at 6.68 ° ± 0.2 °, 13.39 ° ± 0.2 °, 19.65 ° ± 0.2 °, 20.26 ° ± 0.2 °, 22.45 ° ± 0.2 °, 24.80 ° ± 0.2 °, 25.01 ° ± 0.2 °, 26.19 ° ± 0.2 °, 26.61 ° ± 0.2 ° and 28.79 ° ± 0.2 °; or where the crystalline form is Form C, which has a powder X-ray diffraction pattern (XRPD) comprising peaks expressed in degrees 2θ at 5.39 ° ± 0.2 °, 13.25 ° ± 0, 2nd, 16.00 ° ± 0.2 °, 17.27 ° ± 0.2 °, 21.33 ° ± 0.2 °, 21.92 ° ± 0.2 °, 22.53 ° ± 0, 2nd, 23.47 ° ± 0.2 °, 26.56 ° ± 0.2 °, 26.87 ° ± 0.2 °, 29.41 ° ± 0.2 ° and 32.22 ° ± 0, 2nd; or where the crystalline form is Form H, which has a powder X-ray diffraction pattern (XRPD) comprising peaks expressed in degrees 2θ at 7.58 ° ± 0.2 °, 10.29 ° ± 0, 2nd, 12.00 ° ± 0.2 °, 19.07 ° ± 0.2 °, 19.93 ° ± 0.2 °, 20.78 ° ± 0.2 °, 21.33 ° ± 0, 2nd, 21.48 ° ± 0.2 °, 24.76 ° ± 0.2 °, 25.59 ° ± 0.2 °, 25.82 ° ± 0.2 °, 26.01 ° ± 0, 2nd and 26.58 ° ± 0.2 °; or where the crystalline form is Form I, which has a powder X-ray diffraction pattern (XRPD) comprising peaks expressed in degrees 2θ to 9.41 ° ± 0.2 °, 17.59 ° ± 0, 2nd, 21.37 ° ± 0.2 °, 21.72 ° ± 0.2 °, 22.15 ° ± 0.2 °, 22.50 ° ± 0.2 °, 23.90 ° ± 0, 2nd, 24.59 ° ± 0.2 °, 24.99 ° ± 0.2 °, 26.32 ° ± 0.2 °, 27.09 ° ± 0.2 °, 29.68 ° ± 0, 2nd and 30.53 ° ± 0.2 °.
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