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filingDate 2012-06-05-04:00^^<http://www.w3.org/2001/XMLSchema#date>
grantDate 2018-03-14-04:00^^<http://www.w3.org/2001/XMLSchema#date>
inventor http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_03d1ab49b9be39baf0fbc2de6832d744
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publicationDate 2018-03-14-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber ES-2659162-T3
titleOfInvention Production process of bicyclic compound through an iminium salt
abstract A process for producing a mixture of a compound represented by the general formula (I) and a compound represented by the general formula (II): ** Formula ** in which the substituent is defined as follows: R1: a hydrogen atom or a C1-C6 alkyl group, the process (1) comprising reacting a compound represented by the general formula (III) with an allyl halide to produce a compound represented by the general formula (IV): ** Formula ** in which each substituent is defined as follows: R1: a hydrogen atom or a C1-C6 alkyl group, R2: a C1-C6 alkyl group, and X: a halogen atom, (2) reacting the compound represented by the general formula (IV) with malonic acid in the presence of a base or a base and a catalyst to produce a compound represented by the general formula (V): ** Formula ** in which the substituent is defined as as follows: R1: a hydrogen atom or a gr or C1-C6 alkyl, and (3) heating the compound represented by the general formula (V) in the presence of an acid anhydride and a tertiary amine to produce the mixture of the compound represented by the general formula (I) and the compound represented by the general formula (II).
priorityDate 2011-06-08-04:00^^<http://www.w3.org/2001/XMLSchema#date>
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