| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_12a9e9ce63eb0bbf3658453fb50a6d9b |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D209-34 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D209-34 |
| filingDate |
2008-12-02-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate |
2018-03-08-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_0164bf19cc9c1ebd72e480b31e8f28c3
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_a8a3cc4af679995262839a602f379544
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_3b5c38b4313a65ed44c756928141aa84
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_bb6be688e756564bc68486ce19fed313
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_ab8eb27caad1cf5157b36ee33c39c438
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_ea72debfc6bb7ea1bbc85a1130f6385e
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_e233a2bacb3d4185612f86ffc2c9616e
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_0d73a029308671f8b5203bfd667820df |
| publicationDate |
2018-03-08-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
ES-2658091-T3 |
| titleOfInvention |
Procedure for the manufacture of an indolinone derivative |
| abstract |
Process for the manufacture of a compound of the formula ** Formula ** comprising the step of reacting a compound of the formula ** Formula ** with a compound of the formula ** Formula ** in protic or aromatic solvents or in mixtures of these solvents with highly polar solvents at a temperature not less than 50 ° C under reflux conditions, characterized in that the compound of formula ** Formula ** is obtained by dechloroacetylation catalyzed by a base of a compound of formula ** Formula ** in protic solvents at temperatures of about 70 ° C at room temperature using organic or inorganic bases as catalyst. |
| priorityDate |
2007-12-03-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |