| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_8e7adbac0cfee713b5c67b9c0f26b5a5 |
| classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K9-1652
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K9-0085
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/Y10S260-31 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K9-1647
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K9-0024
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K47-36 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K9-16
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K9-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K47-42
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K47-36
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K47-02 |
| filingDate |
2011-03-29-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate |
2018-02-20-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_4d00f768e5f76c0bd89d70e83b05108a
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_ef3c34c660d2ef3092f732b3789f9f58 |
| publicationDate |
2018-02-20-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
ES-2655592-T3 |
| titleOfInvention |
Compositions and methods for improved retention of a pharmaceutical composition at a local administration site |
| abstract |
A composition comprising: a releasable bioactive agent, a retention vehicle polymer, and a crosslinking agent for in-place crosslinking of the retention vehicle polymer in a subject, and a delivery vehicle, wherein the carrier polymer is Retention is a polymer that can be crosslinked to form a polymeric network that retains the releasable bioactive agent, in which the delivery vehicle is a biodegradable polymeric microparticle, and in which the crosslinking agent is present in the delivery vehicle that allows controlled or prolonged release of the crosslinking agent and provides a prolonged dose of the crosslinking agent for continuous crosslinking of the retention vehicle polymer. |
| priorityDate |
2010-03-29-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |