abstract |
A process for preparing a chiral compound comprising an R form or an S form of a glycosphingolipid of formula (1), ** (See formula) ** wherein R1 is -OH, X is an alkyl group, R3 is -OH or H, R4 is -OH or H and R5 is aryl, substituted aryl, heteroaryl or substituted heteroaryl, or a pharmaceutically acceptable salt thereof, wherein the compound of formula 1 is prepared: (a) contacting a compound of formula (6): ** (See formula) ** where PG is a hydroxyl protecting group and LG is a labile group of formula: ** (See formula) ** ... |