| abstract |
A pharmaceutical composition comprising: fimasartan, a pharmaceutically acceptable salt thereof, a hydrate thereof or a solvate thereof; hydrochlorothiazide, a pharmaceutically acceptable salt thereof, a hydrate thereof or a solvate thereof; and a binder; pharmaceutical composition that can be obtained by: the preparation of a mixture comprising fimasartan, a pharmaceutically acceptable salt thereof, a hydrate thereof or a solvate thereof and hydrochlorothiazide, a pharmaceutically acceptable salt thereof, a hydrate thereof or a solvate of it; the preparation of granules by mixing the mixture with a binder solution in which a binder is dissolved so that it has a viscosity of 20 mPa⋅s at 1,000 mPa⋅s at 25 ° C; and the preparation of an uncoated tablet containing the granules. |