http://rdf.ncbi.nlm.nih.gov/pubchem/patent/ES-2651523-T3
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_f21c1009c60308a64b8e7dc0bb989632 |
| classificationCPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K38-00 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P7-02 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K14-755 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K38-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K14-755 |
| filingDate | 2013-02-14-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 2018-01-26-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_d5f3186aabda571cc88e21228823e8d1 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_e53bd74d8d74d721c11a8ba5a27949c9 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_cfe3cfb30b3d0440d56bdcdb6dddfa57 |
| publicationDate | 2018-01-26-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | ES-2651523-T3 |
| titleOfInvention | Von Willebrand Factor variants that have improved Factor VIII binding affinity |
| abstract | A polypeptide comprising a modified von Willebrand Factor (FvW), wherein the amino acid sequence of said modified FvW has at least one mutation within the D 'domain in relation to the amino acid sequence of the wild type FvW D' domain as shown in SEQ ID NO: 31, and wherein the affinity of the binding of said polypeptide comprising a modified FvW, with Factor VIII (FVIII) is greater than that of a reference polypeptide, wherein the amino acid sequence of said reference polypeptide is identical to the amino acid sequence of said polypeptide comprising a modified FvW except that the amino acid sequence of the D 'domain of the reference polypeptide is identical to SEQ ID NO: 31. |
| priorityDate | 2012-02-15-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 105.