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http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/B01J47-00
filingDate 1961-02-23-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationDate 1961-05-01-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber ES-265128-A1
titleOfInvention A PROCEDURE FOR THE SEPARATION OF ANTIBIOTICS
abstract Neomycin B or Neomycin C is separated from a mixture thereof by elution of a mixture of isomeric Neomycins B and C, adsorbed on a carboxylic acid ion exchange resin, with aqueous solutions of an alkaline pH of successively increasing concentration of alkali. A specified ion exchange resin is "Amberlite" IRC-50 (Registered Trade Mark) in the ammoniacal form and specified aqueous alkaline solutions are N/4 and N solutions of ammonium hydroxide. The separated Neomycins B and C may be further purified by successive precipitation from methanol or decolourisation by treatment with animal charcoal.
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type http://data.epo.org/linked-data/def/patent/Publication

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