Predicate |
Object |
assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_6b4a80ac02f1ecd0e698ec665e9b36b6 |
classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N15-63 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K14-755 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12P21-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K1-22 |
classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12P21-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K14-755 |
filingDate |
2007-02-23-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
grantDate |
2018-01-23-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_2b8fa21d5a985e995b7dcf6e82bc113f http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_935170919994c40a6293ff3b6b1247e9 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_924cf51acf7986f93393a37d8e09be3f http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_7835958f416dd0286b507bd3858c53d9 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_3280d369a98b74c90be0fc79ab7ceb9e http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_df2a46b9a93ab80d681597cfa31eb3b4 |
publicationDate |
2018-01-23-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber |
ES-2651028-T3 |
titleOfInvention |
Process to produce and purify factor VIII and its derivatives |
abstract |
The use of dextran sulfate to reduce or block the activities that cleave Factor VIII of certain or certain proteases from culture media of CHO cells and to increase the homogeneity of Factor VIII molecules produced in a process for the production of Factor VIII in CHO cells adapted to a serum-free medium that is supplemented with dextran sulfate, where the average molecular weight of said dextran sulfate is 20 to 5000 kDa. |
priorityDate |
2007-02-23-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type |
http://data.epo.org/linked-data/def/patent/Publication |