| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_3120ae9cab5bb4831f0cc16288966367 |
| classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K38-00 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P25-28
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P9-12
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P9-10
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K14-575
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P3-10
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P3-04
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P3-06
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P1-04
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P1-14 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K14-575 |
| filingDate |
2013-04-19-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate |
2017-11-02-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_63ab6574bf97a729099223dcee0c06ad
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_ff26d3bf23456ab350f7e29b116015d5
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_12f54402b66621acbe183c5d70bd9ea8 |
| publicationDate |
2017-11-02-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
ES-2640285-T3 |
| titleOfInvention |
Human amylin analogs |
| abstract |
A polypeptide that is an analog of SEQ ID NO: 1 that has a selectivity of approximately 10-fold or greater for binding to the human amylin receptor with respect to binding to the human calcitonin receptor and in which: (a) said analog SEQ ID NO: 1 comprises a proline residue at position 21; wherein the amino acid sequence numbering of the analog corresponds to the amino acid numbering sequence of SEQ ID NO: 1; and (b) wherein the polypeptide has at least one substituent attached to at least one of its amino acid residues and, optionally, (c) wherein the polypeptide has an IC50 in a human amylin receptor binding assay of approximately 1200 pM or less and is selected from the group consisting of any one of the polypeptides presented in Table 3. |
| priorityDate |
2012-04-19-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |