http://rdf.ncbi.nlm.nih.gov/pubchem/patent/ES-2638179-T3
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_dbaced0995cda76fea038c684318a8fe |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D471-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D487-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-519 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-5377 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P35-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P35-00 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-519 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P35-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D487-00 |
| filingDate | 2014-01-15-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 2017-10-19-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_d54d319f64a3ab91c6790a69f7ffed85 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_9c8c75a07d857a5ec0f95d249f14b142 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_6efb81a92d89531f5ac561b6a8f7efab http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_4be4bda579046945c4afb3561ea44f77 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_8309273a408cac9d0feef37af35f20a9 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_5f06637d651ead069ab39d423d0fce24 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_a6ed99a1d891e1602683eceaee930aa3 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_36965b7585d3fb4ed50d1c5b4d467716 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_0238b8461e640f4f5ff6fecccf74817e http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_b1895d449525792f1fec04a7564a8cbb http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_fc15791154e1eab4a4872b0fafb24bdd http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_713081135b59af85bdce63b6342fbce5 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_e930be77b41f5568e333506a644a5f1b http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_c3ef8258b36e0f300f9b8dc61f88a2de http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_429d9090922db3f2dce23fbdfc220509 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_843769e039b7d07704b04a79e182b1b7 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_b47a7b1b68eb23104a7da2947d182501 |
| publicationDate | 2017-10-19-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | ES-2638179-T3 |
| titleOfInvention | Substituted pyrrolopyrimidine compounds, compositions thereof, and methods of treatment therewith |
| abstract | A compound of formula (I): ** Formula ** and pharmaceutically acceptable salts, tautomers, stereoisomers, enantiomers and isotopologists thereof, wherein: R1 is substituted or unsubstituted C1-8 alkyl, substituted or unsubstituted C3-8 cycloalkyl , or substituted or unsubstituted non-aromatic heterocyclyl; R2 is substituted or unsubstituted aryl, or substituted or unsubstituted heteroaryl; R3 is substituted or unsubstituted heterocyclyl or substituted or unsubstituted aryl, and L is O; provided that the compound is not 4 - [[trans-3- (methylamino) cyclobutyl] oxy] -N- (1-methyl-1 H -pyrazol-4-yl) -5- (pyridin-3-yl) - 7H-pyrrolo [2,3-d] pyrimidin-2-amine, N- [trans-3 - [[2 - [(1-methyl-1H-pyrazol-4-yl) amino] -5- (2-pyridinyl ) -7H-pyrrolo [2,3-d] pyrimidin-4-yl] oxy] cyclobutyl] -2-Propenamide, N-methyl-N- [trans-3 - [[2 - [(1-methyl-1H- pyrazol-4-yl) amino] -5- (3-pyridinyl) -7H-pyrrolo [2,3-d] pyrimidin-4-yl] oxy] cyclobutyl] -2- Propenamide, N- [trans-3- [ [2 - [(1,3-dimethyl-1H-pyrazol-4-yl) amino] -5- (2-pyridinyl) -7H-pyrrolo [2,3-d] pyrimidin-4-yl] oxy] cyclobutyl] -N-methyl-2- Propenamide, N-methyl-N- [trans-3 - [[5- (1-methyl-1H-pyrazol-3-yl) -2 - [(1-methyl-1H-pyrazole- 4-yl) amino] -7H-pyrrolo [2,3-d] pyrimidin-4- yl] oxy] cyclobutyl] -2-Propenamide, N-methyl-N- [trans-3 - [[2 - [(1 -methyl-1H-pyrazol-4-yl) amino] -5- (2-pyridinyl) -7H-pyrrolo [2,3-d] pyrimidin-4-yl] oxy] cyclobutyl] -2- Propenamide, N-methyl -N- [trans-3 - [[5- (1-methyl-1H-pyrazol-4-yl) -2 - [(1-methyl-1H-pyrazol-4-yl) amino] -7H-pyrrolo [2 , 3-d] pyrimidin-4- yl] oxy] cyclobutyl] -2-Propenamide, N- [c is-3 - [[2 - [(1-methyl-1H-pyrazol-4-yl) amino] -5- (3-pyridinyl) -7H-pyrrolo [2,3-d] pyrimidin-4-yl] oxy ] cyclobutyl] -2-Propenamide or 1 - [(3R, 4R) -3-methoxy-4 - [[[2 - [(1-methyl-1H-pyrazol-4-yl) amino] -5- (2- pyridinyl) -7H-pyrrolo [2,3-d] pyrimidin-4-yl] oxy] methyl] -1-pyrrolidinyl] -2-Propen-1-one. |
| priorityDate | 2013-01-16-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
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